Ankylosing spondylitis in HLA-B27-positive individuals: use in diagnosis.
نویسندگان
چکیده
منابع مشابه
extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis
Objective-To investigate the potential influence of the HLA-linked LMP2 gene on disease susceptibility in HLA-B27 individuals with ankylosing spondylitis (AS). Methods-A polymorphic CfoI restriction enzyme site in the coding region of the LMP2 gene was evaluated in genomic DNA samples from 193 white and 49 Chinese B27 individuals with well documented AS, 97 of whom had had acute anterior uveiti...
متن کاملASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN
Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.
متن کاملHLA-B27 and Ankylosing Spondylitis
Ankylosing spondylitis (AS) is a chronic inflammatory disease with potential disabling outcomes. Clinically, patients presented with inflammatory lower back pain, enthesis and alternated buttock pain (van der Linden & van der Heijde, 1998). Bernard Corner (16661698) was the first physician who published the clinical features of AS in his medical thesis (Baker & Weisman, 2006). In the late 19th ...
متن کاملHLA B27 and risk of ankylosing spondylitis.
'Noble, W C, and Naidoo, J, British Journal of Dermatology, 1978, 98, 481. 2 Porthouse, A, et al, Lancet, 1976, 1, 20. 3Ayliffe, G A J, et al, Journal of Clinical Pathology, 1977, 30, 40. 4Lacey, R W, Journal of Medical Microbiology, 1971, 4, 73. 5 Selwyn, S, and Chalmers, D, British J3ournal of Dermatology, 1965, 77, 349. 6 British Medical3Journal, 1978, 1, 1573. 7British Medical3Journal, 1977...
متن کاملassociation of hla-b27 with ankylosing spondylitis in isfahan, iran
using a standard microcytotoxicity (nih) technique of tissue typing, the hla-b27 antigen was identified in 30 out of 34 patients (hh.2%) with classical ankylosing spondylitis (as), compared to 6 out of 70 controls (h.6%) (p < 0.005). we also found this antigen in 8 out of 76 (10.5%) patients with non-as arthritis.
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ژورنال
عنوان ژورنال: BMJ
سال: 1979
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.6156.125-b